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Author

R. Nguyen

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Review Open access Sep 2026

Modelling missing modalities in multi-omics clinical outcome prediction

Multi-omics integration has become central to precision medicine, yet in real-world clinical cohorts, complete multi-layer profiling is rarely achieved. Cost, assay failure, and evolving study design frequently produce block-wise modality missingness, where entire omics layers are absent for subsets of patients. This...

R. Nguyen, F. Vafaee · 0 citations
Preprint Jul 2026

Harmonised benchmarking of foundation models for single-cell and spatial transcriptomics reveals context-dependent generalisation

This benchmark provides practical guidance for model selection and argues that future models should be judged by biological generalisation, interpretability and perturbation-grounded validity, not by scale or leaderboard performance alone.

S. Chen, Roxana Zahedi, Lucy Chhuo et al. · 0 citations

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