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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

R. Nicholas

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2 papers indexed here

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Open access Aug 2026

Genetic subtypes of multiple sclerosis severity are uncoupled from inflammatory lesion burden

Determinants of long-term disability in multiple sclerosis (MS) remain incompletely understood, with clinical course varying greatly among individuals. Recent integrative genetic models have identified genomic clusters associated with divergent disability trajectories. Here, we integrated clinical, genetic, and postmor...

G. Abbadessa, K. Kreft, O. Howell et al. · 0 citations
Open access Aug 2026

FCGR3A Polymorphism Controls B-Cell Repopulation Kinetics in People With Multiple Sclerosis Treated With Ocrelizumab

Background and Objectives Fc gamma receptor 3A (FCGR3A) V158F polymorphism has been shown to modify the response to anti-CD20 therapy across several autoimmune diseases. Ocrelizumab (OCR), an anti-CD20 agent, suppresses inflammatory activity in multiple sclerosis (MS), yet whether FCGR3A V158F polymorphism affects its...

G. Abbadessa, U. Chianese, Claudia Russo et al. · 0 citations

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