Osteoarthritis (OA) is a leading cause of disability worldwide, characterized by progressive joint degeneration driven by extracellular matrix (ECM) breakdown, chondrocyte apoptosis, and chronic low-grade inflammation. Despite the availability of several pharmacological and non-pharmacological interventions, no current...
Raffaella Rosy Vescio, M. Fiordalisi, L. Ambrosio et al.· Journal of Functional Morpho...· 0 citations
PURPOSE
To compare residual symptoms, function and patient satisfaction following unrestricted kinematic alignment (KA) versus mechanical alignment (MA) in primary total knee arthroplasty (TKA). It was hypothesized that KA would reduce residual symptoms and improve function and satisfaction.
METHODS
A retrospective c...
Stefano Campi, G. Giurazza, E. Franceschetti et al.· Knee Surgery, Sports Traumat...· 0 citations
STUDY DESIGN
Systematic review and meta-analysis.
SUMMARY OF BACKGROUND DATA
Postoperative pain management in spine surgery remains a significant challenge, often involving general anesthesia (GA) and associated complications. Locoregional anesthesia (LRA) has gained attention for its potential benefits in this conte...
G. Papalia, F. Russo, G. Pascarella et al.· Clinical Spine Surgery· 0 citations
Osteoarthritis (OA) is among the leading causes of disability worldwide, yet its pathogenesis remains incompletely understood. Once considered a "non-inflammatory" degenerative disorder, OA is now recognized as a condition driven by chronic low-grade inflammation. Emerging evidence implicates gut dysbiosis as a modifia...
Augusto Ferrini, Alessandro Del Monaco, B. Zampogna et al.· Orthopedic Reviews· 0 citations
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