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Author

R. Parchem

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Aug 2026

Oncogenic KRAS Rewires mRNA Stability and Translation through AGO2-Mediated Disruption of the miRNA pathway.

KRAS mutations occur in over 90% of pancreatic ductal adenocarcinomas (PDACs). Despite recent advances in targeting oncogenic KRAS, tumors eventually acquire resistance. A more comprehensive understanding of the mechanisms connecting KRAS signaling to tumor progression could facilitate the development of effective ther...

Z. Yang, Angelina S. Bortoletto, Mara G. Cardenas et al. · 0 citations

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