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Open access Sep 2026

Central Adiposity and Inflammation Mediate the Association Between Ultraprocessed Food Intake and Cardiovascular Disease Risk.

BACKGROUND Higher consumption of ultraprocessed foods (UPFs) has been consistently associated with increased cardiovascular disease (CVD) risk, but the biological pathways underlying this relationship remain incompletely understood. OBJECTIVES The study aims to examine whether body composition, systemic inflammation,...

Amier Haidar, Spencer Flynn, R. Rikhi et al. · 0 citations
Open access Aug 2026

Joint associations of Interleukin-6 and apolipoprotein B with major adverse cardiovascular events in the UK biobank.

AIMS The relative contributions of inflammatory and atherogenic lipoprotein pathways to residual cardiovascular risk remain unclear. We examined the joint and independent associations of interleukin-6 (IL-6) and apolipoprotein B (ApoB) with major adverse cardiovascular events (MACE) and mortality. METHODS Among 34,06...

P. Cheon, J. McParland, Sean Doherty et al. · 1 citation
Review Open access Aug 2026

Obesity, lipids, inflammation, and healthy aging.

Cardiovascular disease (CVD) is the leading cause of death and disability globally. Thus, prevention efforts aimed at reducing CVD events allow for greater functional independence and wellbeing over the course of life. Low-density lipoprotein-cholesterol is causally associated with atherosclerosis and is the primary ta...

R. Rikhi, Michael D. Shapiro · 0 citations

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