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R. Risques

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Open access Oct 2026

Dysregulation of epithelial differentiation architecture underlies field cancerization in head and neck cancer

Head and neck squamous cell carcinoma (HNSCC) has exceptionally high recurrence rates, exceeding 50%, contributing to mortality and morbidity. This recurrence rate is proposed to be due to field cancerization, a phenomenon where tumor-adjacent “field” tissue that appears histologically normal harbors molecular changes...

Claire B. Mills, Yin Huang, Chan-Mi Lee et al. · 0 citations

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