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R. Ritschard

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Open access Sep 2026

Single-cell tracking reveals tumor-reactive T cell plasticity during melanoma TIL therapy.

Adoptive cell therapy with tumor-infiltrating lymphocytes (TILs) induces durable responses in metastatic melanoma, yet the clonal and transcriptional dynamics governing tumor-reactive T cell fate during ex vivo expansion and after transfer remain poorly understood. Here, we perform longitudinal single-cell RNA and T ce...

M. Sandholzer, Clara Serger, Alessia G. Liner et al. · 0 citations

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