Formulation and Characterization of Lipidic Vesicles Utilizing CCD for Enhanced Permeation of Phenylephrine HCl for Prevention of CIA.
INTRODUCTION Chemotherapy-induced alopecia (CIA) is a common and distressing side effect of cancer therapy. Phenylephrine hydrochloride can reduce follicular exposure to chemotherapeutic drugs through localized vasoconstriction, but its topical effectiveness is limited by poor skin penetration. Invasomal nanocarriers p...