Review
Open access
Aug 2026
GLP-1 receptor agonists for Alzheimer’s disease: Lessons from trials and translational challenges
Although GLP-1 receptor agonists show strong mechanistic rationale and supportive epidemiological signals for neuroprotection, large randomized trials in symptomatic AD have yielded negative clinical outcomes and do not support the therapeutic use in AD.
R. Stringhi, Alessandro Padovani, Elena Marcello
· Cell Reports Medicine · 0 citations