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Author

R. Suryanarayanan

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2 papers indexed here

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Oct 2026

Crystallization Behavior of Amorphous Solid DispersionsRole of Nucleation and Nucleation Density

The Tnose for nucleation (i.e., the temperature of the maximum nucleation rate without any crystal growth) of flurbiprofen-polyvinylpyrrolidone amorphous solid dispersions (ASDs) was determined using the time−temperature−transformation (TTT) diagram. Varying levels of nucleation were induced in ASDs by annealing for...

Bhushan Munjal, Snehal Shukla, Ai-Fang Li et al. · 0 citations
Sep 2026

Design of Stable Dual-Polymer Amorphous Solid Dispersions: Role of Thermodynamics and Kinetics

This dual-polymer approach provided a basis for designing amorphous solid dispersions with high drug loading and improved physical stability thanks to a synergistic mechanism where HPMCAS provided resistance to nucleation by increasing the activation energy barrier, while PVP/PVPVA kinetically lowered the attempt jump...

N. K. Krishna Kumar, John Patani, R. Suryanarayanan · 0 citations

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