Review
Open access
Sep 2026
Tissue-Resident Macrophages: Linking Physiology and Inflammation in Infection
Macrophages are found in every tissue in the body, and their importance goes far beyond clearing pathogens. Developmental studies have shown that many macrophage populations originate during embryogenesis, persist through self-renewal, and adopt transcriptional and functional programs defined by their tissue environmen...
M. E. Cardozo, T. M. Cirilo, Isabela de Brito Duval et al.
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