In this large cohort, higher circulating omega-3 fatty acid levels, including DHA, were associated with lower all-cause mortality, and the relevance of circulating fatty acid profiles in diverse genetic and dietary contexts is highlighted.
Edgar Denova-Gutiérrez, N. Tintle, Heidi T. M. Lai et al.· Clinical Nutrition ESPEN· 0 citations
Smoking and alcohol use increase disease risk through metabolic disruption, vascular damage, and chronic inflammation. Plasma-based nuclear magnetic resonance (NMR) metabolomics can profile lipoproteins, amino acids, and inflammatory biomarkers linked to lifestyle-related disease risk.
We examined cross-se...
T. Hubbard, E. Trichia, J. Alegre-Díaz et al.· Lipids in Health and Disease· 0 citations
Abstract To fully understand the causes of human disease worldwide, large blood based prospective studies are needed in a range of populations with different healthcare settings and exposures to environmental and genetic risk factors. The Mexico City Prospective Study, updated in this cohort profile, was established in...
J. Emberson, J. Alegre-Díaz, J. Berumen et al.· BMJ Medicine· 1 citation
Overall, this study provides an experimental design to study between-ancestry genetic effects and identifies significant ancestry differences for height, type 2 diabetes and metabolic traits in a genetically diverse population from Mexico City.
Si-Qi Wang, J. Berumen, A. Vergara-Lope et al.· Nature· 0 citations
The primordial role of metabolic pathways and adipokines as therapeutic targets for HF management is highlighted, and six cardiomyopathy genes were novel for HF and associated with cardiac structure and function.
D. Rasooly, G. Peloso, C. Giambartolomei et al.· medRxiv· 0 citations
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