Author

R. Upadhyay

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Review Jul 2026

A guide to CAR T cell therapies: development, current status and future prospects.

The key discoveries that laid the foundations for CAR T cell therapies are summarized and a broad overview of the current principles of CAR design, their clinical development and emerging strategies aimed at enhancing efficacy, broadening indications and achieving durable immune control across disease types are provided.

H. Rafei, R. Upadhyay, Padmanee Sharma · Nature reviews. Immunology · 3 citations