Author

R. Văruţ

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Review Open access Sep 2026

Plant-Derived Control of Postprandial Glycemia: α-Amylase, α-Glucosidase, and the Incretin-DPP-4 Interface

Postprandial hyperglycemia can be modified before absorbed glucose reaches the circulation. Plant-derived compounds may slow starch hydrolysis through α-amylase and intestinal α-glucosidases, stimulate glucagon-like peptide-1 (GLP-1) release, or preserve incretin activity through dipeptidyl peptidase-4 (DPP-4) inhibiti...

Pirscoveanu Denisa Floriana Vasilica, D. Trașcă, A. Kamal et al. · Pharmaceuticals · 0 citations

Review Open access Aug 2026

From Plant Chemistry to Reproducible Antidiabetic Products: A Critical Review of Molecular Targets, Clinical Evidence, and Translational Gaps

Diabetes mellitus results from insulin resistance, progressive pancreatic β-cell dysfunction, dysregulated hepatic and adipose metabolism, oxidative stress, and inflammation. Plant-derived compounds can modulate several of these processes, yet pharmacological breadth does not necessarily produce a reproducible therapy....

Pirscoveanu Denisa Floriana Vasilica, D. Trașcă, A. Kamal et al. · Molecules · 0 citations

Review Open access Aug 2026

From FGFR3 Hyperactivation to Disease-Modifying Therapy in Pediatric Achondroplasia: Molecular Mechanisms, Clinical Evidence, and Emerging Treatments

Achondroplasia is increasingly understood as a disorder of dysregulated growth plate signaling rather than solely a condition of reduced stature and vosoritide provides clinical proof that pharmacological modulation of FGFR3-related signaling can improve growth velocity.

R. Șerban, Andreea-Mădălina Mituț-Velișcu, Alexandra-Aurora Dumitra et al. · Children · 0 citations