Author

R. Virmani

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Open access Oct 2026

Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure.

Controlling hyperlipidemia has reduced but not eliminated atherosclerotic cardiovascular disease (ASCVD) as a major cause of human mortality. Here, we report that loss of the immunoregulatory gene GTPase of immunity-associated protein 6 (Gimap6) in mice causes an inflammatory vasculopathy and accelerated atherosclerosi...

Chen Xiang, Kaja Arusha, Danielle A. Springer et al. · Cell · 0 citations

Open access Oct 2026

Patient-Level Perivascular Adipose Tissue Density Aggregation and Plaque Progression: Plaque-Free vs Plaque-Adjacent Segments.

BACKGROUND Perivascular adipose tissue (PVAT) density on coronary computed tomography angiography (CTA) reflects pericoronary inflammation, but measurements adjacent to existing plaques may be confounded by local inflammatory signaling from the plaque itself-a form of reverse causation. Whether systematically comparing...

Sang-Eun Lee, J. Sung, D. Andreini et al. · JACC Cardiovascular Imaging · 0 citations