Open access
Aug 2026
Structural Characterization of Native RNA Polymerase II Transcription Complexes and Nucleosomes in Drosophila melanogaster
This study shows that native Pol II transcription complexes are isolated directly from Drosophila melanogaster embryos by using a robust one-step affinity purification and by using cryo-EM resolve multiple functional states of the Pol II transcription complex and nucleosome.
Natalie L. Venette-Smith, R. Vishwakarma, Varun Venkatakrishnan et al.
· Nature Communications · 0 citations