The HIPC Project and the ImmuneSpace platform demonstrate the feasibility and benefits of a structured approach to representing human immunological studies to elucidate system-level phenomena.
Kerstin Westendorf, M. Kojima, James A. Overton et al.· Journal of Immunology· 0 citations
A CDM for the Adaptive Immune Receptor Repertoire Knowledge Commons was designed based upon the Ontology for Biomedical Investigations, a community standard for scientific data integration, and the LinkML data modeling language was used for implementation.
Scott Christley, Felix Breden, Kevin A. Burns et al.· Journal of Immunology· 0 citations
Chronic viral infections are ubiquitous in humans, with individuals carrying multiple viruses that can reactivate during physiological stress, including severe illness1. Notably, SARS-CoV-2 infection has been shown to reactivate chronic viruses such as Epstein–Barr virus and cytomegalovirus, yet the full extent, tempor...
Cole P. Maguire, Jing Chen, Nadine Rouphael et al.· Nature· 3 citations
CEDAR’s current capabilities, report on progress in curation, database development, and tool availability, and outline the opportunities and challenges ahead for expanding its scope and utility to the cancer research community are described.
Zeynep Koşaloğlu-Yalçın, Ibel Carri, Daniel Marrama et al.· Frontiers in Oncology· 0 citations
Revising all immune receptor records to produce resolved, standardized, and analysis-ready receptor data will enable researchers to seamlessly query large-scale repertoires for receptors with experimentally verified specificity in the IEDB, link orphan sequences to known targets, and support cross-repository studies of...
Lonneke Scheffer, Eve Richardson, R. Vita et al.· Journal of Immunology· 0 citations
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