Open access
Jul 2026
Systematic functional genetic analysis of cell-substrate adhesion
This work defines the requirements for cell-substrate adhesion in cultured human cells using orthogonal, large-scale functional genetic approaches and identifies established and uncharacterized regulators of adhesion, including genes involved in mitosis, focal adhesions, actin regulation, and membrane trafficking.
Kaitlyn Manzer, Kuan-Chung Su, Matteo Di Bernardo et al.
· bioRxiv · 0 citations