Associations between glucolipid metabolic indices with the risk and progression of cardiovascular-kidney-metabolic syndrome in MASLD: evidence from the UK biobank
The predictive performance of biomarkers reflecting insulin resistance, inflammation, and metabolic dysregulation in individuals with MASLD is compared to identify key determinants of CKM progression and assess the rationale for an expanded Cardiovascular -Kidney-Metabolic-Liver (CKML) paradigm.