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R. Westerink

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Review Open access Sep 2026

Extrapolation steps in quantitative in vitro to in vivo extrapolation to advance in vitro-based chemical risk assessment for human health

The transition towards Next Generation Risk Assessment (NGRA) aims at increasing human relevance and efficiency of chemical risk assessment, by using human-based in vitro and in silico methods. Quantitative in vitro to in vivo Extrapolation (QIVIVE) is central to this approach and enables the derivation of health-based...

M. J. M. Benschop, J. Minnema, E. Kasteel et al. · 0 citations

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