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Author

R. Yokoyama

2 papers indexed here

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Open access Sep 2026

307. A new nanoformulation of a brain-penetrating VIPR2 antagonist peptide for the treatment of schizophrenia

Abstract Background Both preclinical and clinical studies have demonstrated a strong link between high expression/overactivation of vasoactive intestinal peptide receptor 2 (VIPR2) and schizophrenia. We recently reported on a brain-penetrant formulation of the VIPR2 antagonist peptide KS-133, which was found to restore...

Y. Ago, Z. Jin, D. Koan et al. · 0 citations
Open access Sep 2026

286. Restoration by ketamine metabolites of cognitive and affective prosocial behaviors in a mouse model of depression

Abstract Background The execution of prosocial behaviors requires the ability to accurately understand and infer others’ affective states. Impairments in prosocial functioning have been shown to be associated with the pathology of several psychiatric disorders. In particular, individuals with depression exhibit reduced...

R. Yokoyama, M. Matsumi, S. Asano et al. · 0 citations

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