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Author

Rachel Massalee

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2 papers indexed here

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Oct 2026

Beta-2 adrenergic receptor in CD8+ T cells inhibits GVHD through transcriptional modulation of differentiation and exhaustion.

Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective therapy for selected hematologic diseases. However, graft-versus-host disease (GVHD) limits broader application of allo-HCT. The catecholaminergic sympathetic nervous system modulates immune cells. Beta-2 adrenergic Receptor (β2AR) acts as an immu...

Sayon Basu, Rachel Massalee, H. Mustapha et al. · 0 citations
Review Open access Aug 2026

The survival motor neuron protein: structure, functions, stability, and therapeutic targeting

This review examines the regulatory mechanisms that control SMN protein stability, collectively termed proteostasis, with a focus on how post-translational modifications coordinate with the ubiquitin-proteasome system and the autophagy-lysosomal pathway to govern protein turnover and clearance.

Bradley R. Smith, Rachel Massalee, Mason Mayer et al. · 0 citations

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