Self-Assembled Ufasomes of Unsaturated Fatty Acids: Mechanisms, Characterization, and Drug Delivery Potential.
Ufasomes-vesicular systems formed from long-chain unsaturated fatty acids such as oleic acid-have re-emerged as cost-effective, biocompatible alternatives to phospholipid liposomes. These bilayered assemblies self-organize at specific pH conditions and efficiently encapsulate both hydrophilic and lipophilic drugs. Thei...