Author

Rahul S. Shinde

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Open access Oct 2026

Apoptotic Cells Promote Tim4+ Macrophage Differentiation Through Direct and Indirect Signaling Pathways

Tissue macrophages are the primary cells responsible for efficiently clearing apoptotic cells, yet how professional efferocyte populations are established remains unclear. Tim4 marks a subset of macrophages across multiple tissues that are highly efferocytic, but the mechanisms governing Tim4 acquisition are poorly und...

Bryan S. Manning, Lin-Na Zhu, Brennah Murphy et al. · bioRxiv · 0 citations

Open access Aug 2026

Malignant epithelial diversification and inflammatory neutrophil remodeling define a transitional stage between tumor cell dissemination and overt metastatic outgrowth in breast cancer

A transitional stage between tumor cell dissemination and overt metastatic outgrowth characterized by malignant epithelial diversification and inflammatory neutrophil remodeling is defined, providing a framework for investigating biomarkers and therapeutic vulnerabilities during this poorly accessible phase of metastat...

R. Pathania, Brian N. Papas, J. Kosak et al. · bioRxiv · 0 citations