Author

Rajan R. Bhawnani

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Open access Sep 2026

Process Analytical Technology (PAT) for Continuous Purification of mRNA via Precipitation and Tangential Flow Filtration.

Continuous downstream processing of messenger ribonucleic acid (mRNA) therapeutics requires purification strategies that are scalable, robust, and capable of removing product- and process-related impurities from in vitro transcription mixtures. Precipitation-based purification coupled with tangential flow filtration (T...

Rajan R. Bhawnani, Maria del Carme Pons Royo, Rohan P. Kadambi et al. · Biotechnology and Bioenginee... · 0 citations

Jul 2026

Impact of Metal Heterogeneity on Multivariate and High-Entropy MOF SBUs.

In chemically complex multimetal systems, how local coordination asymmetry emerges and propagates to define the bulk structural behavior remains fundamentally unresolved. In high-entropy metal-organic frameworks (MOFs), long-range crystallographic order coexists with intrinsic chemical disorder, yet a quantitative rela...

Rajan R. Bhawnani, P. K. Reddy, Meagan R Phister et al. · Journal of the American Chem... · 0 citations