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Rajeev Kishore

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Open access Sep 2026

Iron accumulation in non-transfusion-dependent thalassemia: From molecular mechanisms to clinical practice

Non-transfusion-dependent thalassemia (NTDT) presents a clinical paradox: Patients develop significant iron overload despite minimal transfusion exposure. Iron accumulation occurs primarily through enhanced gastrointestinal absorption driven by a dysregulated hepcidin–ferroportin axis; chronic anemia and ineffective er...

Rahul Garg, Rajeev Kishore · 0 citations

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