Review
Open access
Oct 2026
A Review on Bioanalytical Methods for Quantifying and Structural Determination of Therapeutic Monoclonal Antibodies
Advanced structural characterization incorporates ultra-high-performance liquid chromatography, size-exclusion chromatography, and native high-resolution mass spectrometry across intact, middle-down, and top-down methods to resolve size variants, charge distribution profiles, disulfide linkages, and critical quality at...
Phanisai Yeminedi, Murali Karthik Jalla, Bhavya Sri Kakarla et al.
· Journal of Pharma Insights a... · 0 citations