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Author

Ralph Röth

2 papers indexed here

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Open access Oct 2026

KCNQ1 disruption alters human neuronal development through mitochondrial and insulin signalling pathways

KCNQ1 encodes a voltage-gated potassium channel implicated in peripheral and neurological disorders, but its role in human neurodevelopment remains unclear. We generated KCNQ1 knockout (KO) human induced pluripotent stem cells and differentiated them into neural stem cells (NSCs) and cortical neurons. KCNQ1-deficient N...

Dorothea Schall, B. Guler, Siamand Alibrahim et al. · 0 citations
Open access Sep 2026

Small extracellular vesicles from the plasma of head and neck cancer patients induce dysfunctional T cell phenotypes.

The findings suggest that plasma sEVs contribute to systemic immune modulation in HNC by inducing dysfunctional T-cell phenotypes and underscores the need for further investigation into their relevance for immunotherapeutic strategies in HNC.

Luisa Tengler, Edwin K. Jackson, K. Bieback et al. · 0 citations

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