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Ramon Sotomayor-Zárate

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Open access Oct 2026

5-HT2A receptor activation induces CB1-dependent presynaptic inhibitory long-term depression in the nucleus accumbens core

The serotonin 2A receptor (5-HT2A) is a Gq/11-coupled receptor implicated in reward processing, neuropsychiatric disorders, and the actions of serotonergic psychedelics. Although 5-HT2A activation has been shown to engage endocannabinoid (eCB) signaling in several brain regions, its role in inhibitory synaptic plastici...

Camila Estay-Olmos, Koyam Morales-Weil, Juan Ahumada et al. · 0 citations

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