Author

Rao Mo

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Open access Aug 2026

3Dloop-FPSSM: Predicting Protein–Protein Interactions by Fusing 3D Local Optimal Oriented Pattern and Folded Position-Specific Scoring Matrix

This study introduces a novel sequence-based framework for PPI prediction, which combines position-specific scoring matrices (PSSMs), 3D local optimal orientation patterns (3Dloop), and histogram gradient boosting (HistGB) and shows that the approach provides a reliable and efficient solution for PPI prediction.

Fangfang Bai, Dan Liu, Guangxian Wang et al. · Algorithms · 0 citations