Dose-Dependent Hepatotoxicity of Zinc Oxide Nanoparticles in Rats: Oxidative Stress, Apoptosis, and Dysregulation of Hepatic miR-122, miR-34a, and miR-21
Zinc oxide nanoparticles (ZnO NPs) are widely used in biomedical, agricultural, and industrial applications, raising concerns about their potential hepatotoxicity. This study investigated the effects of 28-day oral ZnO NP exposure on hepatic function, oxidative stress, apoptosis, inflammatory signaling, and microRNA ex...