Jul 2026
The bacterial quorum-sensing molecule 2’-aminoacetophenone reprograms macrophage metabolism and sustains histone lactylation for persistence 2253661
Findings uncover a previously unrecognized QS-regulated metabolic—epigenetic axis through which PA manipulates host immunity, highlighting lactate metabolism as a potential therapeutic target for combating chronic Pseudomonas infections.
Arijit Chakraborty, Arijit Chakraborty, Shifu Aggarwal et al.
· Journal of Immunology · 0 citations