IN SILICO DESIGN AND MOLECULAR DYNAMICS EVALUATION OF 2-ARYL-SUBSTITUTED BENZOXAZOLE DERIVATIVES AS POTENTIAL EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS
Objective: The epidermal growth factor receptor (EGFR) is a clinically established molecular target that plays a key role in the initiation and progression of multiple human cancers. This study aimed to rationally design and evaluate a series of 2-aryl-substituted benzimidazole, benzothiazole, and benzoxazole derivativ...