Author

Ravi K. Dinesh

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#explainable ai Review Open access Sep 2026

AutoScreen: AI Co-Scientist System for Target Discovery in Functional Genomics

Target discovery in functional genomics remains largely manual and time-consuming, lacking systematic tools for efficient and reproducible gene-level hypothesis generation. We introduce AutoScreen, an AI co-scientist system supporting target discovery through both Pre-screen Design, which constructs perturbation librar...

Yuan-Hao Qu, Xu-Feng Liu, Xiao-Tong Wang et al. · bioRxiv · 0 citations

Open access Aug 2026

Surfaceome CRISPR activation screening uncovers ligands regulating tumor sensitivity to NK cell killing

Natural killer (NK) cell-based immunotherapies are promising for cancer treatment due to their ability to eliminate cancer cells independently of antigen presentation and “off-the-shelf” utility. However, molecular determinants governing tumor susceptibility to NK cytotoxicity remain incompletely understood. Here we em...

Ravi K. Dinesh, Xiaotong Wang, Imran A. Mohammad et al. · Nature Communications · 0 citations