Sep 2026
Quality by design-assisted development of an intranasal Shikonin-loaded Mucoadhesive microemulsion for enhanced brain delivery: optimization, characterization, and Pharmacodynamic evaluation in a schizophrenia model.
Preliminary evidence is provided supporting the potential of the optimized intranasal shikonin-loaded mucoadhesive microemulsion for central delivery and modulation of schizophrenia-like behavioral abnormalities, but pilot-scale/large-scale manufacturing feasibility and scale-up validation remain to be established befo...
Pavan Kumar Inuganti, K. Gandla, Lalitha Repudi et al.
· Bioorganic chemistry (Print) · 0 citations