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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Rebecca Hinrichs

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Review Open access Aug 2026

Putative gatekeepers of incoming DNA: 3' exonucleases in natural transformation and bacterial evolution.

Natural transformation is a key mechanism of bacterial adaptation in which exogenous DNA (eDNA) is taken up, processed into single-stranded DNA (ssDNA), and integrated into the genome. While earlier studies primarily focused on uptake mechanisms, transport proteins, and recombination processes, exonucleases were long r...

Rebecca Hinrichs · 0 citations
Open access Aug 2026

Molecular insights into the promiscuous Ap4N hydrolase YqeK

These findings establish YqeK as a central regulator of dinucleotide homeostasis and RNA metabolism and provide the structural framework for Ap4N recognition by HD-domain phosphohydrolases.

Renuka Dharani Shivakumar, Natalie Happel, Fabiana Burchert et al. · 0 citations

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