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Author

Rebecca L. Harper

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Open access Aug 2026

Establishment of human induced pluripotent stem cell lines and isogenic gene-corrected controls from three patients with prolidase deficiency.

These iPSC lines are valuable models to help investigate the pathomechanism of prolidase deficiency and are reprogrammed into induced pluripotent stem cell (iPSC) lines and additionally generated isogenic controls using CRISPR-Cas9 genome editing.

R. Suri, Kevin Emmerich, Sahana Manohar-Sindhu et al. · 0 citations
Open access Aug 2026

Tissue-specific metabolomics in experimental HFpEF reveals hepatic remodelling modulated by SGLT2 inhibition

It is suggested that extra-cardiac metabolic pathways, particularly liver-centered mechanisms, may contribute to the therapeutic benefits of SGLT2 inhibitors in HFpEF and provide new insights into inter-organ metabolic regulation.

M. Kiyar, Ruth R Magaye, Shanae Bailey et al. · 0 citations

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