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Rebecca Lewandowski

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Review Open access Aug 2026

Beyond stool: sampling context and inferential scope in gut mechanistic studies

SUMMARY Human gut microbiome research still relies heavily on fecal sampling because stool is noninvasive, scalable, repeatable, and essential for population-level and longitudinal studies. These strengths have made stool central to human microbiome science, but fecal output is not a neutral representation of every int...

Rebecca Lewandowski · 0 citations
Open access Aug 2026

The multi-omics fallacy in microbiome science

A model-to-mechanism burden of proof is proposed that distinguishes prediction from explanation, imputation from observation, attribution from causality, cross-layer coherence from mechanism, and diagnostic performance from biological validity to strengthen, not constrain, computational microbiome science.

Rebecca Lewandowski · 0 citations

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