Rebekah C. Gullberg

A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation.

Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained...