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Reda M. S. Korany

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Oct 2026

Neuroprotective Effects of Bauhinia variegata Flower Extract against D-Galactose-Induced Age-Related Cognitive Impairment: Modulation of the Oxidative Stress-endoplasmic reticulum Axis.

ETHNOPHARMACOLOGICAL RELEVANCE Bauhinia variegata is widely used in traditional medicine for the management of disorders associated with inflammation, oxidative stress, and nervous system dysfunction. The presence of flavonoids and phenolics supports its ethnopharmacological relevance to cognitive impairment, both repo...

Naglaa M. Ammar, Zeinab A. El-Gendy, Asmaa S. Abd Elkarim et al. · 0 citations
Open access Oct 2026

Vildagliptin attenuates thioacetamide-induced hepatic fibrosis in rats: associations with AMPK/SIRT1/Nrf2 and STAT3/TGF-β1 signaling.

OBJECTIVE Liver fibrosis is a progressive consequence of chronic injury with limited treatment options. Vildagliptin (Vilda), a dipeptidyl peptidase-4 inhibitor, possesses antioxidant and anti-inflammatory properties, but its effects on thioacetamide (TAA)-induced liver fibrosis are not fully characterized. This study...

Mohannad A. Almikhlafi, May A. Alsayb, Sara A. Almadani et al. · 0 citations
Aug 2026

Linagliptin attenuates cisplatin-induced cardiotoxicity in rats via modulation of the SIRT1/AMPK/Nrf2 signaling pathway

Linagliptin demonstrates potent cardioprotective effects against cisplatin-induced toxicity, primarily through modulation of the SIRT1/AMPK/Nrf2 signaling pathway, thereby resulting in reduced oxidative stress and inflammation.

M. Alsugoor, N. Alsuhaymi, Bassim M. S. A. Mohamed et al. · 0 citations

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