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Refugio Cruz-Trujillo

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Open access Sep 2026

The Role of 5-HT1A and 5-HT7 Receptors in Anxiety-like Behavior in Mice Treated with Subchronic Atorvastatin

The polypharmacology of statins includes indirect interactions with the serotonergic system, particularly with the 5-HT1A and 5-HT7 receptors. Statins influence both the expression and function of these receptors, which may affect the regulation of anxiety. The main objective of this study was to examine the effects of...

J. Espinosa-Raya, Alejandro Trejo-Lazaro, Alfredo Briones-Aranda et al. · 0 citations
Open access Aug 2026

Activation of dopamine D4 receptors in the nucleus accumbens shell increases motivation for palatable food and homeostatic feeding, whereas systemic blockade reduces feeding behavior in rats

Dopamine D4 receptors in the nucleus accumbens shell promote both motivational and consummatory aspects of feeding, and systemic D4 receptor blockade suppresses homeostatic feeding and motivation for palatable food, supporting an important role for D4 receptors in the regulation of feeding behavior.

J. G. Tejas-Juárez, Josué O. Suárez-Ortiz, R. E. Escartín-Pérez et al. · 0 citations

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