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Reinaldo G. Sotomayor

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Open access Sep 2026

Development and Optimization of a Self-Nano-Emulsifying Drug-Delivery System (SNEDDS) of Ibuprofen by Implementing a Box–Behnken Experimental Design

Ibuprofen is a widely used non-steroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and anti-inflammatory activity; however, its low aqueous solubility limits its dissolution rate and, consequently, its oral bioavailability. This study aimed to develop and physicochemically characterize an ibuprofen-lo...

María José Jiménez, Keyner De La Cruz, Reinaldo G. Sotomayor · 0 citations

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