While effective for irregular wounds, traditional hemostatic powders often lack posthydration cross-linking, yielding fragile barriers susceptible to washout under high-pressure hemorrhage. To address this, a novel self-gelling composite powder (GOQL) was developed by incorporating dopamine-grafted gelatin (GelDA), oxi...
Tao Liu, An-Bei Chen, Feng-Ya Jing et al.· ACS Applied Materials and In...· 0 citations
Pancreatic cancer remains a highly lethal malignancy because of delayed diagnosis, dense stromal architecture, limited intratumoral drug penetration, systemic treatment-related toxicity, and frequent postoperative recurrence. These challenges have created a need for functional biomaterials that can be applied locally t...
This study develops an injectable, self-healing hydrogel adhesive that orchestrates wound repair through three aspects of microenvironment regulation that achieves wound closure comparable to sutures with reduced inflammation, offering a promising strategy for high-quality tissue regeneration.
Fengya Jing, Tao Liu, Anbei Chen et al.· Acta Biomaterialia· 0 citations
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