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Review Open access Aug 2026

RCBTB2 in cancer: context-dependent functions and translational boundaries

RCBTB2 (RCC1 and BTB domain-containing protein 2), located at chromosome 13q14, is affected by deletion, amplification, expression change, or gene fusion across the cancers studied to date. The divergent directions of these alterations do not fit a tumor-suppressor model with a fixed direction of action. Here, genetic,...

Chuanhai Cai, Jianjun Du, Li-Ga Tu et al. · 0 citations

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