Author

Ren-peng Zhou

2 papers indexed here

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Open access Sep 2026

Caragana sinica root bioactive fraction ameliorates experimental arthritis by inhibiting synovial inflammatory lesions through targeting HSP90α.

BACKGROUND Rheumatoid arthritis (RA) is a chronic autoimmune disease with synovial inflammatory lesions as the initiating factor and pivotal pathogenic driver, triggering persistent inflammation and progressive joint destruction. While Caragana sinica root has long been used in folk medicine for rheumatic disorders, it...

Ying-Jie Zhao, Ya-Nan Chen, Zi-Hao Wang et al. · Phytomedicine · 0 citations

Review Sep 2026

Reprogramming Autoimmune Immunity via Mitochondrial Quality Control: Mechanisms, Biomarkers, and Windows for Intervention.

SIGNIFICANCE In the case of heterogeneous autoimmune diseases (AIDs), the efficacy of single-pathway immunosuppression is limited, the toxicity is substantial, and the problem of cell type-specific metabolic vulnerability cannot be addressed. MECHANISM New evidence highlights mitochondrial quality control (MQC) as an...

Xiao Chen, Jie Ding, Liu-Qing Meng et al. · International Immunopharmaco... · 0 citations