Exploratory Machine Learning Prioritizes Shared Blood Transcriptional Candidate Genes and Immune Correlates Across Antiphospholipid Syndrome and Systemic Sclerosis
Antiphospholipid syndrome (APS) and systemic sclerosis (SSc) are distinct autoimmune diseases, but both are characterized by immune dysregulation, persistent inflammation, and vascular injury. To explore whether they also share blood transcriptional features, we analyzed peripheral blood datasets from GEO (GSE102215, A...