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Oct 2026

SeqSol-FECS: An Integrated Deep Learning and Structural Modeling Framework for Protein Solubility Engineering

Escherichia coli is widely used as a workhorse for heterologous protein expression. However, insoluble protein expression is frequently encountered. The mechanisms underlying protein solubility remain incompletely understood, limiting the effectiveness of current protein solubility engineering strategies. Here, SeqSo...

Qian Guo, Xiao-Ting Zhou, Ren Zhou et al. · 0 citations

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