Author

Renata G. Almeida

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Open access Aug 2026

Prodrug-like Quinone Containing Two Redox-Active Centers Induces Ferroptosis in Prostate Cancer Cells with Cytotoxic Action Partially Depending on NAD(P)H Quinone Dehydrogenase 1 (NQO1)

Overall, compound 4 highlights the potential of dual-redox quinone platforms to induce ferroptosis, providing a viable lead candidate for novel antineoplastic drug discovery in prostate cancer and other malignancies.

E. N. Mendoza, Maria Fernanda Madrid, P. M. D. da Costa et al. · ACS Omega · 0 citations