Author

Rhonda Cardin

2 papers indexed here

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Open access Aug 2026

Antiviral Activity of Nirmatrelvir Against Contemporary SARS-CoV-2 Variants.

Nirmatrelvir, the active antiviral component of Paxlovid®, was evaluated for potency against 20 genetically diverse and clinically relevant SARS-CoV-2 variants circulating between 2020 and 2024. Robust in vitro antiviral activity was demonstrated against all tested variants, with only modest reductions in susceptibilit...

Irina Yurgelonis, Devendra K. Rai, Jonathan T. Lee et al. · Antiviral Research · 0 citations

Open access Jul 2026

The 5′-Isobutyryl Ester Prodrug of 4′-Thiouridine Inhibits SARS-CoV‑2 Replication in Culture and in a Syrian Hamster Infection Model

iBu TU is highlighted as a promising oral antiviral candidate for treating SARS-CoV-2 infection and significantly reduced viral loads and improved lung health without adverse effects in a Syrian hamster model infected with SARS-CoV-2.

Zhe Chen, F. Amblard, M. Kasthuri et al. · ACS Omega · 0 citations