Open access
Sep 2026
Predicting Methodological Quality of Non-Profit Clinical Trial Protocols: A Multicentre Extension
Introduction. The SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) Statement has long been the international reference for the content of clinical trial protocols, ensuring transparency, methodological rigour and ethical soundness [1]. The recent release of SPIRIT 2025 has updated and expande...
G. Gambini, Daniela Bencardino, Lorenza Sanfilippo et al.
· Epidemiology Biostatistics a... · 0 citations